Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836186 | 0.90 | L3MBTL1 (0.68) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL25009811 | 0.90 | L3MBTL1 (0.82) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL21243071 | 0.90 | LMNA (0.82) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL7282911 | 0.88 | L3MBTL1 (0.73) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL30556174 | 0.87 | L3MBTL1 (0.76) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL25009812 | 0.87 | L3MBTL1 (0.76) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL31161094 | 0.86 | L3MBTL1 (0.75) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL7285050 | 0.86 | L3MBTL1 (0.75) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL7285060 | 0.86 | L3MBTL1 (0.75) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL551716 | 0.84 | L3MBTL1 (1.00) | L3MBTL1LMNAKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885307-A1 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd. (CH) | 2015-06-24 | — | — | EP | claimed |
| WO-2014006585-A1 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2014-01-09 | — | — | WO | claimed |
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |