Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.57 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216788 | 0.90 | XDH (0.58) | XDHGDA | |
| SCHEMBL2346371 | 0.86 | XDH (0.62) | XDHGDA | |
| SCHEMBL2249905 | 0.84 | XDH (0.54) | XDHGDA | |
| SCHEMBL8717515 | 0.82 | XDH (0.61) | XDHGDA | |
| SCHEMBL29767333 | 0.82 | XDH (0.70) | XDHGDA | |
| SCHEMBL15532047 | 0.80 | PNP (0.43) | XDHGDAHPRT1 | |
| SCHEMBL5935074 | 0.80 | XDH (0.78) | XDHGDA | |
| SCHEMBL667798 | 0.78 | XDH (0.84) | XDHGDA | |
| SCHEMBL6751934 | 0.78 | XDH (0.71) | XDHGDA | |
| SCHEMBL1733393 | 0.77 | XDH (0.51) | XDHGDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847201-B1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | UNIV QUEENSLAND (AU) | 2017-08-16 | — | — | EP | disclosed |
| WO-2017100849-A1 | 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-22 | — | — | WO | disclosed |
| US-9200020-B2 | 6-oxopurine phosphoribosyltransferase inhibitors | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-12-01 | — | — | US | disclosed |
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-04-09 | — | — | US | disclosed |
| EP-2847201-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | The University of Queensland (AU) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013166545-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | HPRT1, APRT, TPMT | XDH 25/4885GDA 47/4885HPRT1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.