SCHEMBL667798

SCHEMBL667798

CCCNc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.84
GDA Q9Y2T3 1/20 0.59
POLA1 P09884 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6272738 0.92 XDH (1.00) XDHGDAPOLA1
SCHEMBL5935074 0.91 XDH (0.78) XDHGDAPOLA1
SCHEMBL249649 0.90 XDH (1.00) XDHGDAPOLA1
SCHEMBL8535457 0.89 XDH (1.00) XDHGDAPOLA1
SCHEMBL4384744 0.89 XDH (1.00) XDHGDAPOLA1
SCHEMBL874738 0.88 XDH (0.74) XDHGDAPOLA1
Hydrochloric Acid SCHEMBL258899 0.88 XDH (0.97) XDHGDAPOLA1
Hydrochloric Acid SCHEMBL30610398 0.87 XDH (0.95) XDHGDAPOLA1
SCHEMBL9806979 0.85 XDH (0.71) XDHGDA
SCHEMBL6751934 0.85 XDH (0.71) XDHGDA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447746-A Compound for activating AMPK and application thereof HUAAN MEDICAL CO LTD 2015-03-25 CN claimed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 CN disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-4727955-A1 CYSTEINE-SUBSTITUTED RSV-F PROTEINS GlaxoSmithKline Biologicals S.A. (BE) 2026-04-22 EP disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP disclosed
EP-2451823-A2 COMPOSITIONS AND METHODS FOR ENHANCING PRODUCTION OF A BIOLOGICAL PRODUCT Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
EP-2451940-A1 BIOPROCESSING Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
EP-2451476-A1 CELL-BASED BIOPROCESSING Alnylam Pharmaceuticals, Inc. (US) 2012-05-16 EP disclosed
US-20120046346-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-02-23 US disclosed
WO-2009155504-A9 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-04-08 WO disclosed
WO-2009155504-A2 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-23 WO disclosed
WO-2009149239-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-10 WO disclosed
EP-1017394-B1 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES CANCER REC TECH LTD (GB) 2005-12-07 EP disclosed
US-6303618-B1 ADMINISTERING PURINE COMPOUND WHICH INHIBITS CYCLIC DEPENDENT KINASE ACTIVITY FOR THERAPY OF TUMOR OR OTHER CELL PROLIFERATION DISORDER CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2001-10-16 US disclosed
WO-1999002162-A9 CYCLIN DEPENDENT KINASE INHIBITING PURINE DERIVATIVES CANCER RES CAMPAIGN TECH (GB) 1999-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD XDH 3910/4885GDA 483/4885POLA1 49/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 XDH 4104/4885GDA 1277/4885POLA1 1470/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 XDH 4269/4885GDA 2412/4885POLA1 532/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT XDH 3226/4885GDA 909/4885POLA1 916/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 XDH 2754/4885GDA 1088/4885POLA1 1194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.