Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.48 |
| ▸ | NQO2 | P16083 | 6/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15617046 | 0.89 | TRPV1 (0.54) | TRPV1MTNR1ANQO2MTNR1BNPY5R | |
| SCHEMBL15544456 | 0.89 | TRPV1 (0.54) | TRPV1MTNR1ANQO2MTNR1BNPY5R | |
| SCHEMBL15617246 | 0.89 | TRPV1 (0.54) | TRPV1MTNR1ANQO2MTNR1BNPY5R | |
| SCHEMBL15544210 | 0.89 | MTNR1A (0.48) | TRPV1MTNR1ANQO2MTNR1BNPY5R | |
| SCHEMBL17399092 | 0.87 | TRPV1 (0.46) | TRPV1MTNR1AMTNR1BSLC6A9 | |
| SCHEMBL3103846 | 0.79 | SLC6A9 (0.56) | TRPV1SLC6A9KDM1AMAOAMAOB | |
| SCHEMBL3100894 | 0.77 | TRPV1 (0.45) | TRPV1MTNR1ANQO2MTNR1BSLC6A9 | |
| SCHEMBL7272279 | 0.77 | MTNR1A (0.60) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7272276 | 0.77 | MTNR1A (0.60) | MTNR1ANQO2MTNR1B | |
| SCHEMBL3094550 | 0.77 | TRPV1 (0.45) | TRPV1NPY5RSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2016-05-26 | — | — | US | disclosed |
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2016-05-26 | — | — | US | disclosed |
| US-9227901-B2 | Process for preparing bicyclic amine derivatives | ABBVIE INC. (US) | 2016-01-05 | — | — | US | disclosed |
| US-9227901-B2 | Process for preparing bicyclic amine derivatives | ABBVIE INC. (US) | 2016-01-05 | — | — | US | disclosed |
| EP-2870132-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | AbbVie Inc. (US) | 2015-05-13 | — | — | EP | disclosed |
| US-20140012015-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. | 2014-01-09 | — | — | US | disclosed |
| WO-2014008350-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. (US) | 2014-01-09 | — | — | WO | disclosed |
| WO-2014008350-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | ABBVIE INC. (US) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145197-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | HRH4, HRH3, HRH1 | TRPV1 3747/4885MTNR1A 3378/4885NQO2 2266/4885 |
| US-20140012015-A1 | PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES | HRH4, HRH3, HRH1 | TRPV1 3747/4885MTNR1A 3378/4885NQO2 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.