Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158270 | 0.93 | RAB9A (0.68) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL865349 | 0.91 | RAB9A (0.71) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL6187222 | 0.88 | RAB9A (0.62) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL1222314 | 0.88 | RAB9A (0.62) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL510256 | 0.86 | RAB9A (0.68) | RAB9AMAOBMAOAGSK3BBACE1 | |
| Propionaldehyde SCHEMBL28127099 | 0.85 | RAB9A (0.59) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL5107508 | 0.84 | RAB9A (0.57) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL1164139 | 0.84 | MAOB (0.74) | RAB9AMAOBMAOANR4A2KDM4E | |
| SCHEMBL23223734 | 0.84 | RAB9A (0.69) | RAB9AMAOBMAOAGSK3BBACE1 | |
| SCHEMBL11614936 | 0.84 | RAB9A (0.69) | RAB9AMAOBMAOAGSK3BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011049433-A1 | DIAGNOSIS AND TREATMENT OF PRURITIS | ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2011-04-28 | — | — | WO | disclosed |