SCHEMBL158270

SCHEMBL158270

O=Cc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.68
MAOB P27338 5/20 0.67
MAOA P21397 3/20 0.67
GSK3B P49841 2/20 0.61
BACE1 P56817 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.60
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 1/20 0.60
CYP1A2 P05177 1/20 0.60
PTGS1 P23219 1/20 0.60
SLC6A2 P23975 1/20 0.60
CYP2C19 P33261 1/20 0.60
PTGS2 P35354 1/20 0.60
SLC6A3 Q01959 1/20 0.60
HIF1A Q16665 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
BCHE P06276 1/20 0.59
LCK P06239 1/20 0.58
GAA P10253 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL865349 0.98 RAB9A (0.71) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL6187222 0.95 RAB9A (0.62) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL1222314 0.95 RAB9A (0.62) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL1554529 0.93 RAB9A (0.60) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL510256 0.92 RAB9A (0.68) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL1164139 0.90 MAOB (0.74) RAB9AMAOBMAOAKDM4EALDH1A1
SCHEMBL5107508 0.90 RAB9A (0.57) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL23223734 0.90 RAB9A (0.69) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL11614936 0.90 RAB9A (0.69) RAB9AMAOBMAOAGSK3BBACE1
SCHEMBL1300116 0.90 RAB9A (0.65) RAB9AMAOBMAOAGSK3BBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2645 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-119330890-A 4-Benzyloxy benzene substituted barbituric acid derivative and preparation method thereof, 4-benzyloxy benzene substituted barbituric acid derivative flexible crystal and preparation method and application thereof 山西师范大学 2025-01-21 CN claimed
US-20240239803-A1 SYNTHESIS OF COELENTERAZINE INTERNATIONAL PAPER COMPANY 2024-07-18 US claimed
CN-111116339-B Method for artificially synthesizing curcumin and derivatives thereof 武汉回盛生物科技股份有限公司 2023-07-04 CN claimed
CN-113149942-B Rockwell alcohol phenolic hydroxyl derivative, preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-06-02 CN claimed
EP-4065557-A1 A METHOD FOR PREPARING NOVEL CRYSTALLINE FORMS OF 1-(4-BENZYLOXY-BENZYL)-3-METHYL-THIOUREA Therasid Bioscience Inc. (KR) 2022-10-05 EP claimed
CN-114829337-A Preparation method of novel crystal form of 1- (4-benzyloxy-benzyl) -3-methyl-thiourea 泰希诺德生物科技公司 2022-07-29 CN claimed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN claimed
CN-110085879-B Co9S8Sulfur-nitrogen co-doped carbon composite material and preparation method thereof 中国科学院山西煤炭化学研究所 2021-12-24 CN claimed
CN-108409837-B Glycopeptide compound with anti-drug resistance bacterial activity, preparation method and application thereof 上海来益生物药物研究开发中心有限责任公司 2021-09-24 CN claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
EP-0983228-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-03-08 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
WO-1998050342-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-12 WO claimed
EP-0598756-B1 ESTER COMPOSITION SHELL INT RESEARCH (NL) 1996-06-05 EP claimed
CN-1114106-A Benzylamine derivatives OTSUKA PHARMA CO LTD (JP) 1995-12-27 CN claimed
EP-0260305-B1 QUINOLINYL ETHER TETRAZOLE AS AGENT FOR THE TREATMENT OF HYPERSENSITIVE AILMENTS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-12-16 EP claimed
US-4483861-A Antihypertensive sulfur-containing compounds SANTEN PHARMACEUTICAL CO., LTD. (JP) 1984-11-20 US claimed
EP-0075629-A1 Imidazole derivatives, their preparation, and their pharmaceutical compositions Sumitomo Chemical Industries Ltd. (JP) 1983-04-06 EP claimed
US-4101720-A Degradable plastic OWENS-ILLINOIS, INC. (US) 1978-07-18 US claimed