Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 10/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545870 | 0.86 | RAB9A (0.71) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL1164139 | 0.85 | MAOB (0.74) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL6687219 | 0.84 | MAOB (0.66) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL12577967 | 0.82 | RAB9A (0.62) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL27983208 | 0.80 | RAB9A (0.63) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL31395106 | 0.80 | MRGPRX4 (0.56) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL28652467 | 0.79 | RAB9A (0.55) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL12578082 | 0.79 | MAOB (0.60) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL12578075 | 0.79 | RAB9A (0.63) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL3423658 | 0.79 | MAOB (0.65) | RAB9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011049433-A1 | DIAGNOSIS AND TREATMENT OF PRURITIS | ACADEMISCH ZIEKENHUIS BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2011-04-28 | — | — | WO | disclosed |