Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 7/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983208 | 0.90 | RAB9A (0.63) | RAB9AMAOAMAOBPTPN1ALDH1A1 | |
| SCHEMBL13220846 | 0.89 | MAOB (0.76) | RAB9AMAOAMAOBPTPN1NPC1 | |
| SCHEMBL30399352 | 0.89 | MAOB (0.65) | RAB9AMAOAMAOB | |
| SCHEMBL1347334 | 0.89 | MAOB (0.76) | RAB9AMAOAMAOB | |
| SCHEMBL30398583 | 0.89 | MAOB (0.76) | RAB9AMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL1164139 | 0.89 | MAOB (0.74) | RAB9AMAOAMAOBALDH1A1KDM4E | |
| SCHEMBL3423658 | 0.89 | MAOB (0.65) | RAB9AMAOAMAOB | |
| SCHEMBL2019824 | 0.89 | MAOB (0.76) | RAB9AMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL29464145 | 0.89 | MAOB (0.76) | RAB9AMAOAMAOB | |
| SCHEMBL7958497 | 0.87 | RAB9A (0.64) | RAB9AMAOAMAOBLCKF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |