Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15545971 | 0.92 | MEN1 (0.34) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL15545048 | 0.92 | MAPT (0.41) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL15546246 | 0.89 | PTGER4 (0.36) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL15545544 | 0.87 | MEN1 (0.37) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL5157396 | 0.83 | MAPT (0.39) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| Hydrochloric Acid SCHEMBL6271312 | 0.82 | MAPT (0.38) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL2930426 | 0.81 | MAPT (0.40) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL2926193 | 0.80 | MEN1 (0.40) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| Hydrochloric Acid SCHEMBL5477140 | 0.80 | MAPT (0.40) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL14785400 | 0.79 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1APAF1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345653-B2 | Dye composition comprising a cationic meta-phenylenediamine | L'OREAL (FR) | 2016-05-24 | — | — | US | claimed |
| US-20150143638-A1 | DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE | L'OREAL (FR) | 2015-05-28 | — | — | US | claimed |
| EP-2867212-A1 | DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE | L'Oréal (FR) | 2015-05-06 | — | — | EP | claimed |
| WO-2014005900-A1 | DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE | L'OREAL (FR) | 2014-01-09 | — | — | WO | claimed |
| WO-2014005900-A1 | DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE | L'OREAL (FR) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150143638-A1 | DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE | TYR, MAOA, CUTA | SMN1; SMN2 3482/4885MEN1 293/4885APAF1 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.