⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16859908 | 1.00 | ALDH1A1 (0.39) | — | |
| SCHEMBL1861083 | 1.00 | — | — | |
| SCHEMBL18030203 | 1.00 | — | — | |
| SCHEMBL27641218 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL156118 | 0.76 | — | — | |
| SCHEMBL245241 | 0.76 | — | — | |
| SCHEMBL156117 | 0.76 | — | — | |
| SCHEMBL28999926 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL9156886 | 0.72 | — | — | |
| SCHEMBL9027113 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304095-B | N-aryl-N-arpropargyl-aromatic acetamide compound and pharmaceutical application thereof | ZHEJIANG UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-120117999-A | Fluorotranilast derivatives and medical application thereof | 中国药科大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-117304095-A | N-aryl-N-arpropargyl-aromatic acetamide compound and pharmaceutical application thereof | 浙江大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-113402412-B | (E) Method for synthesizing (E) -beta-fluoroacrylamide derivative | 温州大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-113402412-B | (E) Method for synthesizing (E) -beta-fluoroacrylamide derivative | 温州大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-113402412-A | (E) Method for synthesizing (beta) -fluoroacrylamide derivative | 温州大学 | 2021-09-17 | — | — | CN | disclosed |
| WO-2016133935-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. (US) | 2016-08-25 | — | — | WO | disclosed |
| US-20150196585-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS AND USES THEREOF | VIFOR (INTERNATIONAL) LTD. (CH) | 2015-07-16 | — | — | US | disclosed |
| EP-2874633-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | Relypsa, Inc. (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014015240-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
| WO-2014015244-A1 | COMPOSITIONS COMPRISING CROSSLINKED CATION-BINDING POLYMERS | SORBENT THERAPEUTICS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |