Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | CETP | P11597 | 3/20 | 0.52 |
| ▸ | UBE2N | P61088 | 3/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707678 | 0.79 | HMGCR (0.45) | LMNA | |
| SCHEMBL28450410 | 0.76 | PTPN7 (0.42) | THRB | |
| SCHEMBL30088469 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL7584060 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL29389418 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL31268366 | 0.76 | PTPN7 (0.42) | THRB | |
| SCHEMBL7749492 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL31112881 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL31314896 | 0.76 | PTPN7 (0.47) | MAPTPOLBBLMKDM4EMEN1 | |
| SCHEMBL31682163 | 0.75 | PTPN7 (0.42) | MAPTPOLBBLMKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
| WO-2013177121-A2 | IDENTIFICATION AND QUANTIFICATION OF INTACT GLYCOPEPTIDES IN COMPLEX SAMPLES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | CYP2D6 4407/4885MAPT 4762/4885SPHK1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.