Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 20/20 | 0.74 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585432 | 1.00 | SLC5A2 (0.74) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL13278518 | 0.89 | SLC5A2 (0.75) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL155302 | 0.89 | SLC5A2 (0.75) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL158025 | 0.86 | SLC5A2 (0.64) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL23992427 | 0.86 | SLC5A2 (0.81) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL22783104 | 0.85 | SLC5A2 (1.00) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL13468780 | 0.85 | SLC5A2 (1.00) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL8587960 | 0.85 | SLC5A2 (1.00) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL12714462 | 0.85 | SLC5A2 (1.00) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 | |
| SCHEMBL17772218 | 0.85 | SLC5A2 (1.00) | SLC5A2SLC5A1ABCB11ADORA3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651658-B2 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | MITSUBISHI TANABE PHARMA CORP (JP) | 2020-08-12 | — | — | EP | claimed |
| EP-2252289-B1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2019-10-23 | — | — | EP | claimed |
| US-20180282363-A1 | GLUCOPYRANOSIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-10-04 | — | — | US | claimed |
| US-20160108078-A1 | GLUCOPYRANOSIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2016-04-21 | — | — | US | claimed |
| US-20140371162-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-12-18 | — | — | US | claimed |
| US-8853385-B2 | Combination therapy comprising SGLT inhibitors and DPP4 inhibitors | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-10-07 | — | — | US | claimed |
| US-20140296506-A1 | GLUCOPYRANOSIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-10-02 | — | — | US | claimed |
| US-8785403-B2 | Glucopyranoside compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2014-07-22 | — | — | US | claimed |
| CN-103214471-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2013-07-24 | — | — | CN | claimed |
| EP-1651658-B1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-01-16 | — | — | EP | claimed |
| US-20120058941-A1 | GLUCOPYRANOSIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-08 | — | — | US | claimed |
| US-7943788-B2 | Including the antidiabetic, antiobesity sodium glucose transport inhibitor Canagliflozin (1-( beta -D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene) | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-17 | — | — | US | claimed |
| JP-2011509922-A | — | — | 2011-03-31 | — | — | JP | claimed |
| US-20110059912-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-03-10 | — | — | US | claimed |
| EP-2252289-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-11-24 | — | — | EP | claimed |
| WO-2009091082-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-07-23 | — | — | WO | claimed |
| CN-1829729-A | Novel compounds | TANABE SEIYAKU CO (JP) | 2006-09-06 | — | — | CN | claimed |
| EP-1651658-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2006-05-03 | — | — | EP | claimed |
| US-20050233988-A1 | Novel compounds | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-20 | — | — | US | claimed |
| WO-2005012326-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058941-A1 | GLUCOPYRANOSIDE COMPOUND | UGGT1, B3GAT3, FUT6 | SLC5A2 5/4885SLC5A1 13/4885ABCB11 200/4885 |
| US-20050233988-A1 | Novel compounds | CYP1B1, CYP4B1, CYP2B6 | SLC5A2 472/4885SLC5A1 303/4885ABCB11 24/4885 |
| US-20140371162-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | DPP4, SLC5A1, GLP1R | SLC5A2 5/4885SLC5A1 2/4885ABCB11 430/4885 |
| US-20110059912-A1 | COMBINATION THERAPY COMPRISING SGLT INHIBITORS AND DPP4 INHIBITORS | DPP4, SLC5A1, GLP1R | SLC5A2 5/4885SLC5A1 2/4885ABCB11 430/4885 |
| US-20180282363-A1 | GLUCOPYRANOSIDE COMPOUND | UGGT1, B3GAT3, FUT6 | SLC5A2 5/4885SLC5A1 13/4885ABCB11 200/4885 |
| US-20160108078-A1 | GLUCOPYRANOSIDE COMPOUND | UGGT1, B3GAT3, FUT6 | SLC5A2 5/4885SLC5A1 13/4885ABCB11 200/4885 |
| US-20140296506-A1 | GLUCOPYRANOSIDE COMPOUND | UGGT1, B3GAT3, FUT6 | SLC5A2 5/4885SLC5A1 13/4885ABCB11 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.