Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15560767 | 0.70 | NAMPT (0.34) | — | |
| SCHEMBL21263656 | 0.68 | NOS2 (0.44) | — | |
| SCHEMBL1830089 | 0.68 | — | — | |
| SCHEMBL24866428 | 0.62 | AKT2 (0.44) | — | |
| SCHEMBL32670416 | 0.62 | — | — | |
| SCHEMBL44968 | 0.61 | — | — | |
| SCHEMBL24093930 | 0.61 | — | — | |
| SCHEMBL1751652 | 0.61 | — | — | |
| SCHEMBL14638428 | 0.61 | — | — | |
| SCHEMBL23732868 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854814-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therapeutics, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177559-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2013-11-28 | — | — | WO | disclosed |