Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570545 | 0.74 | PLA2G4A (0.47) | — | |
| SCHEMBL15548482 | 0.70 | PIM1 (0.30) | — | |
| SCHEMBL15549350 | 0.70 | MEN1 (0.40) | NAMPT | |
| SCHEMBL21263656 | 0.68 | NOS2 (0.44) | — | |
| SCHEMBL1989334 | 0.68 | — | — | |
| SCHEMBL1830089 | 0.68 | — | — | |
| SCHEMBL27514365 | 0.68 | — | — | |
| SCHEMBL28795824 | 0.67 | — | — | |
| SCHEMBL4159772 | 0.67 | HTR7 (0.44) | NAMPT | |
| SCHEMBL1986516 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2854814-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | Corcept Therapeutics, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177559-A2 | HETEROARYL-KETONE FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. (US) | 2013-11-28 | — | — | WO | disclosed |