Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.43 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050393 | 0.90 | HPGD (0.54) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL2412888 | 0.83 | KDM4E (0.96) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL341835 | 0.82 | KDM4E (1.00) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL12270682 | 0.80 | HPGD (0.73) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL1554914 | 0.80 | TSHR (0.73) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL1554880 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL2410144 | 0.77 | KDM4E (0.88) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL12266251 | 0.76 | CYP1A2 (0.67) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL14198827 | 0.76 | KDM4E (0.79) | ALDH1A1HPGDKDM4EMEN1TRPM2 | |
| SCHEMBL12266145 | 0.76 | CYP1A2 (0.79) | ALDH1A1HPGDKDM4EMEN1TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | claimed |
| WO-2011050095-A2 | PREVENTION AND TREATMENT OF POST-OPERATIVE COGNITIVE DYSFUNCTION (POCD) | THE GENERAL HOSPITAL CORPORATION (US) | 2011-04-28 | — | — | WO | disclosed |
| EP-1961756-A1 | NOVEL BISBORON COMPOUND | Japan Science and Technology Agency (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-1444981-A1 | INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS | Mikoshiba, Katsuhiko (JP) | 2004-08-11 | — | — | EP | disclosed |