SCHEMBL341835

SCHEMBL341835

NCCOB(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 1.00
HPGD P15428 2/20 1.00
MAPK1 P28482 2/20 1.00
MEN1 O00255 1/20 1.00
TRPM2 O94759 1/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP3A4 P08684 1/20 1.00
THRB P10828 1/20 1.00
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
ALOX12 P18054 1/20 1.00
KMT2A Q03164 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
ORAI1 Q96D31 1/20 0.48
ORAI2 Q96SN7 1/20 0.48
ORAI3 Q9BRQ5 1/20 0.48
TRPV6 Q9H1D0 1/20 0.48
TAAR1 Q96RJ0 2/20 0.46
LYPLA1 O75608 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2412888 0.98 KDM4E (0.96) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL2410144 0.94 KDM4E (0.88) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL2409329 0.92 KDM4E (0.85) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL12270752 0.90 KDM4E (0.81) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL12266145 0.89 CYP1A2 (0.79) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL14198827 0.89 KDM4E (0.79) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL22832991 0.88 MAPK1 (0.78) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL12266225 0.86 KDM4E (0.73) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL1554914 0.86 TSHR (0.73) KDM4EHPGDMAPK1MEN1TRPM2
SCHEMBL12270682 0.86 HPGD (0.73) KDM4EHPGDMAPK1MEN1TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367371-A1 HYBRID BIOELECTRONIC/ENGINEERED CELL IMPLANTABLE SYSTEM FOR THERAPEUTIC AGENTS DELIVERY AND APPLICATIONS THEREOF UNIV NORTHWESTERN (US) 2025-12-04 US claimed
WO-2025091023-A1 ENGINEERED CELL TRANSFECTED BY ALL-IN-ONE VECTOR FOR THERAPEUTIC AGENTS PRODUCTION AND DELIVERY AND APPLICATIONS THEREOF NORTHWESTERN UNIVERSITY (US) 2025-05-01 WO claimed
CN-119199000-A Thin-layer identification of micro-emulsion for evaluating multiple particles of dyspnea Zu Pa 新疆医科大学 2024-12-27 CN claimed
EP-4444283-A1 SPECIALIZED COMBINATIONS FOR MENTAL DISORDERS OR MENTAL ENHANCEMENT Tactogen Inc. (US) 2024-10-16 EP claimed
WO-2024091700-A1 HYBRID BIOELECTRONIC/ENGINEERED CELL IMPLANTABLE SYSTEM FOR THERAPEUTIC AGENTS DELIVERY AND APPLICATIONS THEREOF NORTHWESTERN UNIVERSITY (US) 2024-05-02 WO claimed
US-11938135-B2 Compositions and methods for treating vascular Ehlers Danlos syndrome and associated disorders THE JOHNS HOPKINS UNIVERSITY (US) 2024-03-26 US claimed
WO-2024033113-A1 ACTIVE AGENT MODULATING THE ACTIVITY OF AN ION CHANNEL FOR USE IN REGULATION OF SKIN PIGMENTATION CUTANEON - SKIN & HAIR INNOVATIONS GMBH (DE) 2024-02-15 WO claimed
EP-4321148-A1 ACTIVE AGENT MODULATING THE ACTIVITY OF AN ION CHANNEL FOR USE IN REGULATION OF SKIN PIGMENTATION CUTANEON - Skin & Hair Innovations GmbH (DE) 2024-02-14 EP claimed
US-20230405136-A1 New Combinations of Boron Compounds and Adjuvants for the Treatment of Pathophysiological Conditions and Cancer and for Muscle Regeneration CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED, M.P. (ES) 2023-12-21 US claimed
WO-2023196235-A1 METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES GLAZIER ALAN NEIL (US) 2023-10-12 WO claimed
WO-2008080409-A1 A METHOD AND KIT FOR TESTING STRESS EFFECTS IN LIVING ORGANISM AARHUS UNIVERSITET (DK) 2008-07-10 WO claimed
WO-2008080410-A1 METHOD AND KIT FOR DETECTING RESISTANCE IN LIVING ORGANISMS AARHUS UNIVERSITET (DK) 2008-07-10 WO claimed
EP-1838678-A1 PROCESS FOR OBTAINING CIZOLIRTINE AND ITS ENANTIOMERS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-10-03 EP claimed
US-7109349-B2 Process for obtaining Cizolirtine and its enantiomers LABORATORIOS DEL DR. ESTEVE, S/A (ES) 2006-09-19 US claimed
US-20060135788-A1 PROCESS FOR OBTAINING CIZOLIRTINE AND ITS ENANTIOMERS LABORATORIOS DEL DR. ESTEVE, S/A (ES) 2006-06-22 US claimed
WO-2006063861-A1 PROCESS FOR OBTAINING CIZOLIRTINE AND ITS ENANTIOMERS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-06-22 WO claimed
EP-1671953-A1 Process for obtaining cizolirtine and its enantiomers LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-06-21 EP claimed
WO-2006029142-A2 METHODS AND SYSTEMS FOR TREATING ASTHMA AND OTHER RESPIRATORY DISEASES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2006-03-16 WO claimed
US-20040259842-A1 Intracellular calcuim concentration increase inhibitors MIKOSHIBA, KATSUHIKO (JP) 2004-12-23 US claimed
EP-1444981-A1 INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS Mikoshiba, Katsuhiko (JP) 2004-08-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259842-A1 Intracellular calcuim concentration increase inhibitors CAB39, BPGM, ORAI1 KDM4E 4858/4885HPGD 1700/4885MAPK1 1089/4885
US-20230405136-A1 New Combinations of Boron Compounds and Adjuvants for the Treatment of Pathophysiological Conditions and Cancer and for Muscle Regeneration MUSK, MBNL1, MYOF KDM4E 4783/4885HPGD 3933/4885MAPK1 474/4885
US-20060135788-A1 PROCESS FOR OBTAINING CIZOLIRTINE AND ITS ENANTIOMERS CYP2E1, MAP2K1, MAP2K5 KDM4E 2413/4885HPGD 800/4885MAPK1 751/4885
US-11938135-B2 Compositions and methods for treating vascular Ehlers Danlos syndrome and associated disorders COL2A1, COL1A1, MMP1 KDM4E 2988/4885HPGD 633/4885MAPK1 4418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.