Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.83 |
| ▸ | PROKR1 | Q8TCW9 | 11/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15549113 | 0.91 | FPR2 (1.00) | FPR2PROKR1LMNA | |
| SCHEMBL15548928 | 0.88 | FPR2 (0.79) | FPR2PROKR1LMNATSHRALDH1A1 | |
| SCHEMBL15549371 | 0.81 | FPR2 (1.00) | FPR2PROKR1LMNA | |
| SCHEMBL15549024 | 0.79 | TSHR (0.61) | FPR2PROKR1LMNATSHRTDP1 | |
| SCHEMBL15549192 | 0.77 | FPR2 (1.00) | FPR2PROKR1 | |
| SCHEMBL15549025 | 0.77 | TSHR (0.59) | FPR2PROKR1LMNATSHRALDH1A1 | |
| SCHEMBL31212431 | 0.75 | EBP (0.70) | LMNATSHRALDH1A1 | |
| SCHEMBL31212435 | 0.75 | EBP (0.70) | LMNATSHRALDH1A1 | |
| SCHEMBL15548661 | 0.75 | PROKR1 (1.00) | FPR2PROKR1 | |
| SCHEMBL15536936 | 0.74 | FPR2 (0.58) | FPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | claimed |
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | claimed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | claimed |
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |