Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032374 | 0.91 | KMT2A (0.67) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL31652507 | 0.86 | KMT2A (0.89) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8046428 | 0.85 | KMT2A (0.91) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL17599913 | 0.85 | KMT2A (0.91) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29792075 | 0.84 | KMT2A (0.90) | KMT2AHTT | |
| SCHEMBL29370234 | 0.84 | KMT2A (0.90) | KMT2AHTT | |
| SCHEMBL178801 | 0.84 | KMT2A (0.90) | KMT2AHTT | |
| SCHEMBL17599909 | 0.84 | KMT2A (0.69) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL23270799 | 0.84 | KMT2A (0.62) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL25834582 | 0.84 | KMT2A (0.56) | KMT2AHDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014018913-A2 | SANTACRUZAMATE A COMPOSITIONS AND ANALOGS AND METHODS OF USE | UNIVERSITY OF CONNECTICUT (US) | 2014-01-30 | — | — | WO | disclosed |