Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554221 | 0.82 | ALDH1A1 (0.48) | EPHX1HPGDSIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5859760 | 0.77 | HSD11B1 (0.45) | CCR2HSD11B1 | |
| SCHEMBL30117192 | 0.77 | HSD11B1 (0.45) | CCR2HSD11B1 | |
| SCHEMBL24745145 | 0.77 | HSD11B1 (0.45) | CCR2HSD11B1 | |
| SCHEMBL28424700 | 0.76 | HSD11B1 (0.41) | CCR2HSD11B1 | |
| SCHEMBL34473728 | 0.76 | HSD11B1 (0.44) | CCR2HSD11B1 | |
| SCHEMBL30722926 | 0.76 | HSD11B1 (0.44) | CCR2HSD11B1 | |
| SCHEMBL19415337 | 0.76 | HSD11B1 (0.44) | CCR2HSD11B1 | |
| SCHEMBL15366822 | 0.76 | HSD11B1 (0.44) | CCR2HSD11B1 | |
| SCHEMBL15366820 | 0.76 | HSD11B1 (0.44) | CCR2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |