Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15993523 | 0.76 | TDP1 (0.39) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL14380333 | 0.76 | TDP1 (0.39) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL1756719 | 0.76 | FFAR3 (0.33) | SMN1; SMN2CHRM2LMNAPOLBALDH1A1 | |
| SCHEMBL16478592 | 0.74 | CA1 (0.42) | SMN1; SMN2TSHRFFAR3 | |
| SCHEMBL463116 | 0.74 | TDP1 (0.38) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL8005614 | 0.74 | MEN1 (0.44) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL22208089 | 0.72 | MAPT (0.33) | SMN1; SMN2CHRM2POLBALDH1A1CHRM4 | |
| SCHEMBL2281546 | 0.70 | SMN1; SMN2 (0.35) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL22115888 | 0.70 | SMN1; SMN2 (0.35) | TDP1EYA2APPACESMN1; SMN2 | |
| SCHEMBL12721519 | 0.70 | SMN1; SMN2 (0.36) | TDP1EYA2APPACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953963-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS | Agency For Science, Technology And Research (SG) | 2015-12-16 | — | — | EP | claimed |
| EP-2855505-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS FIELD | Agency For Science, Technology And Research (SG) | 2015-04-08 | — | — | EP | claimed |
| WO-2014123483-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-08-14 | — | — | WO | claimed |
| WO-2013180649-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS FIELD | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-12-05 | — | — | WO | claimed |
| EP-2953963-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS | Agency For Science, Technology And Research (SG) | 2015-12-16 | — | — | EP | disclosed |
| EP-2855505-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS FIELD | Agency For Science, Technology And Research (SG) | 2015-04-08 | — | — | EP | disclosed |
| WO-2014123483-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-08-14 | — | — | WO | disclosed |
| WO-2013180649-A1 | MIXED MULTIFUNCTIONAL METAL AFFINITY SURFACES FOR REDUCING AGGREGATE CONTENT IN PROTEIN PREPARATIONS FIELD | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-12-05 | — | — | WO | disclosed |
| US-20090182057-A1 | DEUTERATED AMINOGLYCIDAL COMPOUNDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182057-A1 | DEUTERATED AMINOGLYCIDAL COMPOUNDS | ADRB2, GLRB, ADRB1 | TDP1 1337/4885EYA2 1380/4885APP 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.