Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.61 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | RORA | P35398 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548226 | 0.76 | FPR2 (1.00) | FPR2PROKR1 | |
| SCHEMBL229024 | 0.73 | HRH3 (1.00) | FPR2PROKR1HRH3SMN1; SMN2RORA | |
| SCHEMBL29763007 | 0.73 | CDK2 (0.61) | CCNA2CDK2CCNKCDK12CCR6 | |
| SCHEMBL2706929 | 0.73 | HRH3 (0.56) | FPR2PROKR1HRH3MAPTSMN1; SMN2 | |
| SCHEMBL24477559 | 0.72 | KMT2A (0.57) | — | |
| SCHEMBL27213310 | 0.72 | CHRM1 (0.44) | MAPTSMN1; SMN2CCNA2CDK2CCNK | |
| SCHEMBL24477770 | 0.71 | KMT2A (0.47) | CCNA2CDK2CCNKCDK12 | |
| SCHEMBL4236934 | 0.70 | HRH3 (0.70) | FPR2PROKR1HRH3RORARORC | |
| SCHEMBL21887075 | 0.70 | HRH3 (0.85) | FPR2PROKR1HRH3 | |
| SCHEMBL26918782 | 0.69 | CDK2 (0.53) | CCNA2CDK2CCNKCDK12CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | claimed |
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | claimed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | claimed |
| EP-2855449-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | Takeda Pharmaceutical Company Limited (JP) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013179024-A1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-12-05 | — | — | WO | disclosed |