Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15553366 | 1.00 | CRHBP (0.52) | CRHBPCRHR2EPHX1POLBBACE1 | |
| SCHEMBL15552462 | 1.00 | CRHBP (0.52) | CRHBPCRHR2EPHX1POLBBACE1 | |
| Hydrochloric Acid SCHEMBL15559325 | 0.99 | CRHBP (0.51) | CRHBPCRHR2EPHX1POLBBACE1 | |
| SCHEMBL15555286 | 0.90 | EPHX1 (0.63) | EPHX1POLBBACE1BACE2KDM4A | |
| SCHEMBL15554157 | 0.90 | EPHX1 (0.63) | EPHX1POLBBACE1BACE2KDM4A | |
| SCHEMBL15553655 | 0.90 | EPHX1 (0.63) | EPHX1POLBBACE1BACE2KDM4A | |
| SCHEMBL15553297 | 0.89 | EPHX1 (0.51) | EPHX1POLBBACE1BACE2MEN1 | |
| SCHEMBL15553274 | 0.89 | EPHX1 (0.51) | EPHX1POLBBACE1BACE2MEN1 | |
| Hydrochloric Acid SCHEMBL15554159 | 0.89 | EPHX1 (0.61) | EPHX1POLBBACE1BACE2KDM4A | |
| Hydrochloric Acid SCHEMBL15553761 | 0.89 | EPHX1 (0.61) | EPHX1POLBBACE1BACE2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016766-A1 | GUANIDINE DERIVATIVES AS TRPC MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-01-30 | — | — | WO | claimed |
| WO-2014016766-A1 | GUANIDINE DERIVATIVES AS TRPC MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-01-30 | — | — | WO | disclosed |