Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.53 |
| ▸ | IL2 | P60568 | 3/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.51 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15554013 | 0.90 | MAP4K1 (0.53) | MAP4K1IL2ALKTBK1KIT | |
| SCHEMBL15554206 | 0.88 | PIK3CD (0.51) | MAP4K1IL2ALKTBK1KIT | |
| SCHEMBL14977054 | 0.87 | TBK1 (0.68) | TBK1 | |
| SCHEMBL15554849 | 0.86 | MAPK8 (0.54) | MAP4K1IL2ALKTBK1KIT | |
| SCHEMBL14977091 | 0.78 | TBK1 (0.55) | ALKTBK1MAPK8MAPK9MAPK10 | |
| SCHEMBL14975973 | 0.78 | TBK1 (0.57) | ALKTBK1KIT | |
| SCHEMBL14976819 | 0.78 | TBK1 (0.56) | MAP4K1IL2ALKTBK1KIT | |
| SCHEMBL12501111 | 0.78 | PDPK1 (0.48) | ALKTBK1MAPK8MAPK9MAPK10 | |
| SCHEMBL14981860 | 0.77 | TBK1 (0.61) | TBK1 | |
| SCHEMBL14977031 | 0.77 | TBK1 (0.62) | TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014004863-A2 | COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| WO-2014004863-A2 | COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| WO-2014004863-A2 | COMPOUNDS, COMPOSITIONS, AND THERAPEUTIC USES THEREOF | ALZHEIMER'S INSTITUTE OF AMERICA, INC. (US) | 2014-01-03 | — | — | WO | disclosed |