Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706054 | 0.86 | KCNK3 (0.43) | KCNK3KCNK9KMT2ALPAR1LMNA | |
| SCHEMBL43475 | 0.82 | ELANE (0.49) | ELANEALOX15KMT2AKDM4EMEN1 | |
| SCHEMBL28422371 | 0.82 | PPARG (0.44) | ELANEACLYKMT2AKDM4EMEN1 | |
| SCHEMBL15548665 | 0.78 | SCN5A (0.46) | ALOX15NLRP3 | |
| SCHEMBL29484682 | 0.78 | HIF1A (0.52) | ALOX15NLRP3LMNA | |
| SCHEMBL16330807 | 0.76 | SCN5A (0.52) | — | |
| SCHEMBL30791332 | 0.76 | KCNK3 (0.47) | KCNK3KCNK9KMT2AKDM4EMEN1 | |
| SCHEMBL28822603 | 0.75 | KMT2A (0.41) | ELANEACLYALOX15KMT2AKDM4E | |
| SCHEMBL28397404 | 0.75 | FFAR1 (0.40) | KMT2ALPAR1LMNA | |
| SCHEMBL8435546 | 0.75 | ALOX15 (0.55) | ELANEACLYALOX15KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014016766-A1 | GUANIDINE DERIVATIVES AS TRPC MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-01-30 | — | — | WO | disclosed |