SCHEMBL43475

SCHEMBL43475

CCC(=O)Oc1ccccc1C(C)C

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.49
CES2 O00748 1/20 0.48
CYP1A2 P05177 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
ALOX15 P16050 1/20 0.46
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NLRP3 Q96P20 1/20 0.43
ESR1 P03372 1/20 0.42
HIF1A Q16665 1/20 0.42
ACHE P22303 1/20 0.41
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41
LPAR1 Q92633 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7433035 0.87 ELANE (0.47) ELANEKMT2AMEN1ALOX15L3MBTL1
SCHEMBL8434637 0.87 CES2 (0.52) CES2CYP1A2TSHRCYP2C19KMT2A
SCHEMBL1791401 0.86 TSHR (0.52) ELANETSHRKMT2AMEN1ALOX15
SCHEMBL11425288 0.86 KMT2A (0.50) CES2CYP1A2TSHRCYP2C19KMT2A
SCHEMBL15548665 0.84 SCN5A (0.46) ALOX15NLRP3
SCHEMBL28620307 0.84 KMT2A (0.43) CES2CYP1A2TSHRCYP2C19KMT2A
SCHEMBL29484682 0.84 HIF1A (0.52) CYP1A2TSHRALOX15LMNANLRP3
SCHEMBL8435546 0.84 ALOX15 (0.55) ELANEKMT2AMEN1ALOX15L3MBTL1
SCHEMBL5302718 0.84 CES2 (0.47) CES2CYP1A2TSHRCYP2C19KMT2A
SCHEMBL15560740 0.82 ELANE (0.41) ELANEKMT2AMEN1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US disclosed
CN-114206893-A (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN disclosed
US-11274181-B2 Polyimide dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2022-03-15 US disclosed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US disclosed
US-10875946-B2 Polyolefin dispersants and methods of making and using thereof CHEVRON ORONITE COMPANY LLC (US) 2020-12-29 US disclosed
EP-3684842-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
EP-3684894-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP disclosed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US disclosed
WO-2019055984-A1 POLYIMIDE DISPERSANTS AND METHODS OF MAKING AND USING THEREOF CHEVRON ORONITE COMPANY LLC (US) 2019-03-21 WO disclosed
US-20190085129-A1 Polyimide Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC 2019-03-21 US disclosed
EP-2284203-A2 Method for preparation of polyolefins containing exo-olefin chain ends Chevron Oronite Company LLC (US) 2011-02-16 EP disclosed
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2011-02-03 US disclosed
WO-2011014665-A2 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-02-03 WO disclosed
WO-2010083181-A2 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2010-07-22 WO disclosed
US-20100184918-A1 Functionalization of Polyolefins with Phenoxy Derivatives UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-07-22 US disclosed
EP-1781715-A4 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2008-09-10 EP disclosed
US-7420019-B2 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC (US) 2008-09-02 US disclosed
EP-1781715-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS Chevron Oronite Company LLC (US) 2007-05-09 EP disclosed
WO-2006023988-A2 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE COMPANY LLC (US) 2006-03-02 WO disclosed
US-20060041084-A1 Quenching a cationic quasi-living polyolefin polymer system with one or more hindered secondary or tertiary amines CHEVRON ORONITE COMPANY LLC 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028681-A1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS RXFP3, HCAR3, LPAR3 ELANE 4345/4885CES2 1732/4885CYP1A2 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.