Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16367411 | 0.80 | CYP19A1 (0.33) | CYP19A1GUSBHDAC8 | |
| SCHEMBL15560936 | 0.80 | CYP19A1 (0.33) | CYP19A1GUSBHDAC8 | |
| SCHEMBL16367364 | 0.80 | CYP19A1 (0.33) | CYP19A1GUSBHDAC8HDAC6 | |
| SCHEMBL15608185 | 0.75 | CYP19A1 (0.32) | CYP19A1 | |
| SCHEMBL15544163 | 0.74 | CYP19A1 (0.32) | CYP19A1KCNH2 | |
| SCHEMBL16343251 | 0.72 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL16342580 | 0.69 | ALDH1A1 (0.33) | CYP19A1 | |
| SCHEMBL15544616 | 0.69 | PSMD10 (0.35) | — | |
| SCHEMBL15545174 | 0.68 | THRB (0.32) | — | |
| SCHEMBL16367391 | 0.66 | KMT2A (0.38) | MAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793871-A1 | COMPOUNDS AND METHODS FOR SELECTIVE IMAGING AND/OR ABLATION | Auckland Uniservices Limited (NZ) | 2014-10-29 | — | — | EP | disclosed |
| WO-2014007650-A1 | COMPOUNDS AND METHODS FOR SELECTIVE IMAGING AND/OR ABLATION | AUCKLAND UNISERVICES LIMITED (NZ) | 2014-01-09 | — | — | WO | disclosed |