Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | G6PD | P11413 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15564523 | 0.93 | DAO (0.56) | DAOHPGDMAPTKDM4EG6PD | |
| SCHEMBL16968205 | 0.93 | DAO (0.56) | DAOHPGDMAPTKDM4EG6PD | |
| SCHEMBL15564859 | 0.87 | DAO (0.47) | DAOHPGDALDH1A1GRIA1GRIA2 | |
| SCHEMBL15564790 | 0.87 | DAO (0.54) | DAOSIGMAR1L3MBTL1 | |
| SCHEMBL15564464 | 0.87 | DAO (0.52) | DAOHPGDMEN1KMT2AGRIA1 | |
| SCHEMBL15563574 | 0.85 | DAO (0.47) | DAOMEN1ALDH1A1KMT2AHTR2A | |
| SCHEMBL15565356 | 0.85 | DAO (0.47) | DAOHPGDMAPTKDM4EMEN1 | |
| SCHEMBL15563742 | 0.83 | DAO (0.49) | DAOMAPTKDM4EKMT2AGRIA1 | |
| SCHEMBL15563974 | 0.81 | DAO (0.56) | DAO | |
| SCHEMBL15564215 | 0.81 | DAO (0.56) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |