Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16968204 | 0.93 | DAO (0.58) | DAOMEN1KMT2AGRIA1GRIA2 | |
| SCHEMBL16968265 | 0.93 | DAO (0.58) | DAOMEN1KMT2AFFAR1FAAH | |
| SCHEMBL15564834 | 0.91 | DAO (0.54) | DAOMEN1KMT2AGRIA1GRIA2 | |
| SCHEMBL15563742 | 0.88 | DAO (0.49) | DAOKMT2AGRIA1GRIA2GRIA4 | |
| SCHEMBL15564345 | 0.87 | DAO (0.50) | DAOMEN1KMT2AGRIA1GRIA2 | |
| SCHEMBL16968253 | 0.83 | DAO (0.61) | DAOMEN1KMT2AGRIA1GRIA2 | |
| SCHEMBL15564859 | 0.83 | DAO (0.47) | DAOGRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL15565356 | 0.83 | DAO (0.47) | DAOMEN1KMT2AGRIA1GRIA2 | |
| SCHEMBL15564479 | 0.82 | DAO (0.51) | DAOKMT2AGRIA1GRIA2GRIA4 | |
| SCHEMBL15564271 | 0.82 | DAO (0.55) | DAOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |