SCHEMBL15564614

SCHEMBL15564614

CC(C)[C@H]1CC[C@H](C)C[C@@H]1[O]

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 5/20 0.56
TRPA1 O75762 2/20 0.56
EPHX1 P07099 3/20 0.52
KCNA5 P22460 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TRPV1 Q8NER1 3/20 0.38
LMNA P02545 1/20 0.38
NFE2L2 Q16236 1/20 0.37
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL608359 1.00 TRPM8 (0.56) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL7103829 1.00 TRPM8 (0.56) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL30604482 0.77 TRPM8 (0.62) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL10612768 0.76 TRPM8 (0.56) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL767051 0.76
SCHEMBL21349959 0.75 TRPM8 (0.60) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL26770470 0.75 TRPM8 (0.60) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL9080881 0.75 TRPM8 (0.60) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL19719730 0.75 TRPM8 (0.60) TRPM8TRPA1EPHX1KCNA5ALDH1A1
SCHEMBL2761364 0.75 TRPM8 (0.60) TRPM8TRPA1EPHX1KCNA5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014023531-A1 TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2014-02-13 WO disclosed