Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608359 | 1.00 | TRPM8 (0.56) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL15564614 | 1.00 | TRPM8 (0.56) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL30604482 | 0.77 | TRPM8 (0.62) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL10612768 | 0.76 | TRPM8 (0.56) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL767051 | 0.76 | — | — | |
| SCHEMBL21349959 | 0.75 | TRPM8 (0.60) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL26770470 | 0.75 | TRPM8 (0.60) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL9080881 | 0.75 | TRPM8 (0.60) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL19719730 | 0.75 | TRPM8 (0.60) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL2761364 | 0.75 | TRPM8 (0.60) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620969-A | Cyclohexane dicarboxylic acid derivative with bridged ring, and pharmaceutical composition and application thereof | 贵州医科大学 | 2021-11-09 | — | — | CN | claimed |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | claimed |
| CN-113620969-A | Cyclohexane dicarboxylic acid derivative with bridged ring, and pharmaceutical composition and application thereof | 贵州医科大学 | 2021-11-09 | — | — | CN | disclosed |
| WO-2014023531-A1 | TRIFLUOROMETHYLPYRIDINE CARBOXAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | WO | disclosed |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
| EP-0023454-A2 | Process for the preparation of 6,6-dimethyl-4-hydroxy-3-oxabicyclo(3.1.0)hexan-2-one and its ethers of all possible stereoisomeric forms | ROUSSEL-UCLAF (FR) | 1981-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | TRPM8 1269/4885TRPA1 654/4885EPHX1 1827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.