Urea

Urea

SCHEMBL1556486

NC(N)=O.OCP.OCP.OCP.OCP

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
OR51E2 Q9H255 2/20 0.55
ACHE P22303 1/20 0.39
BLM P54132 3/20 0.38
PMP22 Q01453 3/20 0.38
ALOX15 P16050 3/20 0.38
CYP3A4 P08684 3/20 0.38
CYP1A2 P05177 2/20 0.38
HPGD P15428 2/20 0.38
THPO P40225 2/20 0.38
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GMNN O75496 1/20 0.38
USP2 O75604 1/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL1556120 1.00
Urea SCHEMBL2248328 0.76
Urea SCHEMBL8560069 0.74 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL20641124 0.74 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea SCHEMBL411583 0.74
Urea SCHEMBL7756359 0.74 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
SCHEMBL167536 0.74
Urea SCHEMBL8434002 0.74 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE
Urea C 13 SCHEMBL12476878 0.74
Urea SCHEMBL8436158 0.74 LMNA (1.00) LMNAALDH1A1TDP1OR51E2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202720-B2 Flame resistant textile MILLIKEN & COMPANY (US) 2019-02-12 US disclosed
WO-2011049700-A2 FLAME RESISTANT TEXTILE MILLIKEN & COMPANY (US) 2011-04-28 WO disclosed
US-20110092119-A1 FLAME RESISTANT TEXTILE MILLIKEN & COMPANY 2011-04-21 US disclosed