Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565149 | 1.00 | DAO (0.58) | DAOHRH3CYP1A2TAAR1CYP2C19 | |
| SCHEMBL15564051 | 0.87 | DAO (0.57) | DAOTAAR1 | |
| SCHEMBL15563911 | 0.86 | DAO (0.56) | DAOCYP1A2TAAR1CYP2C19 | |
| SCHEMBL15564169 | 0.84 | DAO (0.57) | DAO | |
| SCHEMBL15563710 | 0.83 | DAO (0.58) | DAOHRH3CYP1A2TAAR1CYP2C19 | |
| SCHEMBL15564271 | 0.82 | DAO (0.55) | DAO | |
| SCHEMBL15565204 | 0.81 | DAO (0.50) | DAO | |
| SCHEMBL15564747 | 0.80 | DAO (0.49) | DAOCYP1A2CYP2C19 | |
| SCHEMBL15565177 | 0.80 | DAO (0.49) | DAO | |
| SCHEMBL15564237 | 0.78 | DAO (0.58) | DAOCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |