Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15563911 | 0.93 | DAO (0.56) | DAOMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL16968246 | 0.93 | DAO (0.56) | DAOMEN1KMT2AALDH1A1GRIA1 | |
| SCHEMBL15565204 | 0.87 | DAO (0.50) | DAOMEN1KMT2AALDH1A1GRIA1 | |
| SCHEMBL15565177 | 0.86 | DAO (0.49) | DAOMEN1KMT2AALDH1A1GRIA1 | |
| SCHEMBL15564758 | 0.84 | DAO (0.51) | DAOKMT2AALDH1A1GRIA1GRIA2 | |
| SCHEMBL15565356 | 0.81 | DAO (0.47) | DAOMEN1KMT2AALDH1A1GRIA1 | |
| SCHEMBL16968259 | 0.80 | DAO (0.56) | DAOMEN1KMT2AALDH1A1GRIA1 | |
| SCHEMBL15565182 | 0.80 | DAO (0.58) | DAOCYP1A2CYP2C19 | |
| SCHEMBL15565149 | 0.80 | DAO (0.58) | DAOCYP1A2CYP2C19 | |
| SCHEMBL15563742 | 0.79 | DAO (0.49) | DAOKMT2AGRIA1GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014025993-A1 | INHIBITORS OF D-AMINO ACID OXIDASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-02-13 | — | — | WO | disclosed |