Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1629038 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL21442571 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL15564368 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL16901967 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL15565349 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL1629691 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL18672266 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL16998539 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL16998564 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2ALMNANPC1RAB9A | |
| SCHEMBL14760853 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882719-A2 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014026079-A2 | COMPOSITIONS, METHODS, AND SYSTEMS OF THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-02-13 | — | — | WO | disclosed |