Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16998559 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL1629038 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15565441 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16901882 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15566236 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16998539 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15565322 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15565244 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16901967 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL15564368 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872928-B2 | Diagnostic agent for therapeutic effect on cancer | HAMAMATSU PHOTONICS K.K. (JP) | 2018-01-23 | — | — | US | disclosed |
| US-9872928-B2 | Diagnostic agent for therapeutic effect on cancer | HAMAMATSU PHOTONICS K.K. (JP) | 2018-01-23 | — | — | US | disclosed |
| US-9598399-B2 | Compound suitable for detection of mitochondrial complex-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2017-03-21 | — | — | US | disclosed |
| US-9598399-B2 | Compound suitable for detection of mitochondrial complex-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | HAMAMATSU PHOTONICS K.K. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | HAMAMATSU PHOTONICS K.K. (JP) | 2016-09-08 | — | — | US | disclosed |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2015-08-13 | — | — | US | disclosed |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | HAMAMATSU PHOTONICS K.K. (JP) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256578-A1 | DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER | NOC2L, NOP56, NPM1 | SMN1; SMN2 1322/4885RAB9A 3364/4885NPC1 187/4885 |
| US-20150225368-A1 | COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1 | MT-ND1, MT-CO1, UQCRC1 | SMN1; SMN2 1449/4885RAB9A 2946/4885NPC1 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.