SCHEMBL155666

SCHEMBL155666

O=C(c1ccccc1)c1ccccc1-n1cc(O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O)c2c(Cl)c(Br)ccc21

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HK1 P19367 2/20 0.33
HK2 P52789 2/20 0.33
SLC5A2 P31639 4/20 0.32
SLC5A1 P13866 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LGALS9 O00182 1/20 0.32
LGALS1 P09382 1/20 0.32
LGALS3 P17931 1/20 0.32
LGALS7; LGALS7B P47929 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27856153 0.90 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL155667 0.90 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL155033 0.90 SLC28A3 (0.34) SLC5A2SLC5A1
SCHEMBL155668 0.90 SLC5A2 (0.40) SLC5A2SLC5A1
SCHEMBL154135 0.89 TP53 (0.35) SLC5A2POLB
SCHEMBL156534 0.88 HK1 (0.38) HK1HK2SLC5A2SLC5A1
SCHEMBL153142 0.86 SLC5A2 (0.34) SLC5A2SLC5A1
SCHEMBL153287 0.83 HK1 (0.37) HK1HK2SLC5A2SLC5A1POLB
SCHEMBL154836 0.83 HK1 (0.35) HK1HK2SLC5A2SMN1; SMN2LGALS9
SCHEMBL14058429 0.83 HK1 (0.35) HK1HK2SLC5A2SMN1; SMN2LGALS9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940909-B2 Indicator platform BIOSYNTH AG (CH) 2015-01-27 US disclosed
EP-2427431-B1 NOVEL INDICATOR PLATFORM BIOSYNTH AG (CH) 2013-05-01 EP disclosed
US-20120058503-A1 Novel Indicator Platform BIOSYNTH AG (CH) 2012-03-08 US disclosed
EP-2256103-A1 Novel indicator platform Biosynth AG (CH) 2010-12-01 EP disclosed