Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23022739 | 0.69 | ATM (0.51) | GRIN1GRIN2BMAPK14 | |
| SCHEMBL28292785 | 0.68 | BTK (0.41) | MAPK14 | |
| SCHEMBL23022794 | 0.68 | GRIN2B (0.46) | GRIN1GRIN2B | |
| SCHEMBL28291346 | 0.68 | MEN1 (0.33) | — | |
| SCHEMBL16321611 | 0.65 | PROKR1 (0.53) | — | |
| SCHEMBL4544766 | 0.64 | CCR3 (0.59) | GRIN2B | |
| SCHEMBL2172919 | 0.64 | DAO (0.38) | — | |
| SCHEMBL23022733 | 0.64 | MAOA (0.47) | GRIN1GRIN2B | |
| SCHEMBL31038860 | 0.63 | AURKA (0.34) | — | |
| SCHEMBL28291340 | 0.62 | GPR6 (0.45) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882722-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | Envoy Therapeutics Inc. (US) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014028479-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | ENVOY THERAPEUTICS, INC. (US) | 2014-02-20 | — | — | WO | disclosed |