Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 6/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291346 | 0.83 | MEN1 (0.33) | GPR6CHRM4CCR3HTR2AHTR2C | |
| SCHEMBL20971822 | 0.79 | GPR119 (0.54) | GPR6 | |
| SCHEMBL25145660 | 0.78 | SLC6A4 (0.49) | GPR6KCNH2 | |
| SCHEMBL23022739 | 0.76 | ATM (0.51) | HTR2AKMT2A | |
| SCHEMBL17008795 | 0.74 | GPR6 (0.47) | GPR6 | |
| SCHEMBL26144501 | 0.74 | GPR6 (0.54) | GPR6HTR2AHTR2CKCNH2 | |
| SCHEMBL26144303 | 0.73 | GPR6 (0.56) | GPR6CCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL26143918 | 0.72 | GPR6 (0.54) | GPR6CCR3HTR2AHTR2CKCNH2 | |
| SCHEMBL25133038 | 0.71 | SLC6A9 (0.47) | KCNH2 | |
| SCHEMBL20524624 | 0.70 | GPR6 (0.59) | GPR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |