Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.43 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.43 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929711 | 0.85 | TNFRSF1A (0.46) | MAPTLMNAHTTPARP1HSD17B10 | |
| SCHEMBL143394 | 0.85 | TNFRSF1A (0.46) | MAPTLMNAHTTPARP1HSD17B10 | |
| SCHEMBL155669 | 0.81 | NTRK1 (0.53) | MAPTLMNAHTTPARP1PRKCA | |
| SCHEMBL29930012 | 0.77 | GRIK1 (0.46) | MAPTCYP1A2CYP2A6HSD17B10TP53 | |
| SCHEMBL144090 | 0.77 | MAPT (0.45) | MAPTLMNAHTTCYP1A2CYP2A6 | |
| SCHEMBL143250 | 0.77 | GRIK1 (0.46) | MAPTCYP1A2CYP2A6HSD17B10TP53 | |
| SCHEMBL29930299 | 0.77 | MAPT (0.45) | MAPTLMNAHTTCYP1A2CYP2A6 | |
| SCHEMBL157234 | 0.75 | MAPT (0.45) | MAPTLMNAHTTCYP3A4CYP1A2 | |
| SCHEMBL29929589 | 0.75 | MAPT (0.45) | MAPTLMNAHTTCYP3A4CYP1A2 | |
| SCHEMBL154089 | 0.74 | MAPK14 (0.47) | MAPTLMNAHTTNTRK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |