Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406408 | 0.89 | NTRK1 (0.49) | NTRK1MAPTLMNAHTTPARP1 | |
| SCHEMBL3404138 | 0.85 | NTRK1 (0.46) | NTRK1MAPTLMNAHTTPARP1 | |
| SCHEMBL155671 | 0.81 | MAPT (0.45) | NTRK1MAPTLMNAHTTPARP1 | |
| SCHEMBL3402828 | 0.81 | LMNA (0.44) | NTRK1MAPTLMNAHTTPARP1 | |
| SCHEMBL154801 | 0.75 | LMNA (0.43) | NTRK1MAPTLMNAHTTPARP1 | |
| SCHEMBL28866215 | 0.73 | CYP1A1 (0.59) | MAPTLMNAHTTPRKCAGSK3B | |
| SCHEMBL142563 | 0.72 | NTRK1 (0.48) | NTRK1MAPTLMNAHTTHSD17B10 | |
| SCHEMBL8476962 | 0.71 | NTRK1 (0.52) | NTRK1MAPTLMNAHTTPRKCA | |
| SCHEMBL155750 | 0.70 | IDO1 (0.43) | NTRK1MAPTPRKCAGSK3BTP53 | |
| SCHEMBL29930277 | 0.70 | NTRK1 (0.49) | NTRK1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |