Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15567670 | 1.00 | NPC1 (0.44) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL618344 | 0.97 | PREP (0.41) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL618345 | 0.97 | PREP (0.41) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL619069 | 0.97 | PREP (0.41) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL620744 | 0.89 | PREP (0.40) | NPC1RAB9AHPGDIRAK4ALDH1A1 | |
| SCHEMBL620745 | 0.89 | PREP (0.40) | NPC1RAB9AHPGDIRAK4ALDH1A1 | |
| SCHEMBL15607328 | 0.87 | IRAK4 (0.44) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL16205072 | 0.87 | IRAK4 (0.44) | NPC1RAB9AHPGDIRAK4MEN1 | |
| SCHEMBL15566352 | 0.85 | MAPT (0.42) | HPGDIRAK4MEN1KMT2AALDH1A1 | |
| SCHEMBL15567619 | 0.85 | NPC1 (0.42) | NPC1RAB9AHPGDIRAK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-3593648-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2021-07-14 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| EP-2880031-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2020-06-17 | — | — | EP | disclosed |
| CN-104603132-B | Sweet taste modifier | 弗门尼舍公司 | 2020-02-21 | — | — | CN | disclosed |
| US-9745293-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9687015-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2016-11-17 | — | — | US | disclosed |
| US-9420814-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| US-9138013-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2880031-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC | 2015-01-29 | — | — | US | disclosed |
| US-8877922-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| WO-2014025706-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374020-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NPC1 2736/4885RAB9A 3210/4885HPGD 2426/4885 |
| US-20150031684-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NPC1 2736/4885RAB9A 3210/4885HPGD 2426/4885 |
| US-20170183336-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NPC1 2871/4885RAB9A 3168/4885HPGD 2313/4885 |
| US-20160331013-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NPC1 2871/4885RAB9A 3168/4885HPGD 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.