Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 1.00 |
| ▸ | CHRNA1 | P02708 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503534 | 0.92 | CHRNA7 (0.84) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL7120449 | 0.86 | CHRNA7 (0.75) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL10613844 | 0.82 | CHRNA7 (0.70) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL7508779 | 0.82 | CHRNA7 (0.70) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL14931770 | 0.82 | CHRNA7 (0.70) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL7507814 | 0.81 | CHRNA7 (0.68) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL14606326 | 0.80 | CHRNA7 (0.73) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL6327790 | 0.79 | CHRNA7 (0.71) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL6324205 | 0.79 | CHRNA7 (0.71) | CHRNA7CHRNA1MEN1KMT2ATDP1 | |
| SCHEMBL9889726 | 0.79 | CHRNA7 (0.71) | CHRNA7CHRNA1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857725-B1 | (N-(pyridinylmethyl)-heterocyclic)-ylideneamine compounds as nicotinic acetylcholine receptor binding agents | PFIZER (US) | 2001-07-25 | — | — | EP | claimed |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-9717242-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20160205933-A1 | PEST CONTROL AGENT | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-07-21 | — | — | US | disclosed |
| US-9328068-B2 | N-[1-((6-chloropyridin-3-yl) methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide for control of animal parasitic pests and agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| EP-2984930-A1 | PEST CONTROL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| EP-2631235-B1 | Pest control agent | MEIJI SEIKA PHARMA CO LTD (JP) | 2016-02-10 | — | — | EP | disclosed |
| EP-2959775-A1 | PEST CONTROL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-9073866-B2 | Pest control agent | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-07-07 | — | — | US | disclosed |
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| CN-102076673-A | Novel imino derivative, process for production of same, and pesticide comprising same | KUREHA CORP | 2011-05-25 | — | — | CN | disclosed |
| EP-2305658-A1 | NOVEL IMINO DERIVATIVE, PROCESS FOR PRODUCTION OF THE SAME, AND PESTICIDE COMPRISING THE SAME | Meiji Seika Kaisha, Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-6900202-B2 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1218371-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | SUNTORY LIMITED | 2002-03-07 | — | — | US | disclosed |
| EP-1176141-A1 | HETEROCYCLIC COMPOUNDS HAVING EFFECT OF ACTIVATING NICOTINIC ACETYLCHOLINE $g(a)4$g(b)2 RECEPTOR | SUNTORY LIMITED (JP) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001070733-A2 | DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS | SUNTORY LIMITED (JP) | 2001-09-27 | — | — | WO | disclosed |
| EP-0857725-B1 | (N-(pyridinylmethyl)-heterocyclic)-ylideneamine compounds as nicotinic acetylcholine receptor binding agents | PFIZER (US) | 2001-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172433-A1 | NOVEL IMINO DERIVATIVES, METHODS FOR PRODUCING THE SAME AND INSECTICIDES CONTAINING THE SAME | CNOT9, CBR1, CBR3 | CHRNA7 125/4885CHRNA1 23/4885MEN1 2393/4885 |
| US-20020028809-A1 | Heterocyclic compounds having effect of activating a4beta2 nicotinic acetylcholine receptors | CHRNA2, CHRNA7, CHRNB2 | CHRNA7 2/4885CHRNA1 6/4885MEN1 3855/4885 |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | NR2E1, CROCC, PRMT1 | CHRNA7 1779/4885CHRNA1 1138/4885MEN1 1385/4885 |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | NR2E1, CROCC, PRMT1 | CHRNA7 1779/4885CHRNA1 1138/4885MEN1 1385/4885 |
| US-20030078259-A1 | Di-substituted imineheterocyclic compounds | CHRNA2, CHRNA7, CHRNB2 | CHRNA7 2/4885CHRNA1 6/4885MEN1 2653/4885 |
| US-20160205933-A1 | PEST CONTROL AGENT | RPS4Y1, RPS4X, RDX | CHRNA7 3429/4885CHRNA1 3759/4885MEN1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.