Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 10/20 | 0.49 |
| ▸ | STAT6 | P42226 | 6/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478992 | 0.87 | PTK2 (0.51) | PTK2STAT6CDK4CCND1JAK3 | |
| SCHEMBL12478740 | 0.86 | PTK2 (0.53) | PTK2STAT6CDK4CCND1SYK | |
| SCHEMBL12478260 | 0.80 | PTK2 (0.54) | PTK2STAT6 | |
| SCHEMBL15568488 | 0.80 | PTK2 (0.78) | PTK2 | |
| SCHEMBL17994178 | 0.80 | JAK2 (0.48) | PTK2CDK4CCND1JAK3SYK | |
| SCHEMBL15524830 | 0.79 | PTK2 (0.49) | PTK2 | |
| SCHEMBL12479026 | 0.79 | PTK2 (0.51) | PTK2STAT6 | |
| SCHEMBL14576997 | 0.78 | PTK2 (0.51) | PTK2CDK4CCND1SYK | |
| SCHEMBL14576325 | 0.78 | PTK2 (0.48) | PTK2STAT6CDK4CCND1SYK | |
| SCHEMBL15524693 | 0.78 | JAK3 (0.45) | PTK2JAK3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027199-A1 | FAK AND FLT3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2014-02-20 | — | — | WO | disclosed |