Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590177 | 0.88 | KMT2A (0.40) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL15569517 | 0.84 | CDK8 (0.51) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL15569276 | 0.84 | TSHR (0.49) | TP53LMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL18608743 | 0.83 | PTGS2 (0.50) | LMNAPTGS1ALDH1A1MEN1KMT2A | |
| SCHEMBL15570020 | 0.81 | TP53 (0.51) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL15569711 | 0.80 | GLA (0.47) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL17054058 | 0.79 | POLB (0.54) | TP53LMNASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL15568846 | 0.78 | SMN1; SMN2 (0.39) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL15570257 | 0.77 | TP53 (0.43) | TP53LMNACDK8ACVR1SMN1; SMN2 | |
| SCHEMBL19980500 | 0.77 | CDK8 (0.39) | TP53LMNACDK8ACVR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017032786-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-02 | — | — | WO | disclosed |
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |