Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590180 | 0.90 | MAPT (0.48) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL15569851 | 0.87 | TSHR (0.51) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL15569022 | 0.86 | TSHR (0.50) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL17054065 | 0.85 | PTGS2 (0.49) | MAPTALDH1A1NPC1GAANPSR1 | |
| SCHEMBL15568546 | 0.84 | TP53 (0.48) | SMN1; SMN2LMNAALDH1A1HPGDTP53 | |
| SCHEMBL391742 | 0.78 | KDM5B (0.45) | SMN1; SMN2LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL18590178 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL18590177 | 0.76 | KMT2A (0.40) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL1753231 | 0.75 | ALDH1A1 (0.57) | TSHRSMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL15569660 | 0.75 | KDM5B (0.42) | SMN1; SMN2LMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014031971-A1 | HERBICIDAL PYRIDAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-27 | — | — | WO | disclosed |