SCHEMBL15568682

SCHEMBL15568682

CC1(C)CC(C2CCC(C(=O)O)CC2)CC(C)(C)N1[O]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.42
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C19 P33261 4/20 0.35
LMNA P02545 3/20 0.34
PLG P00747 1/20 0.34
PLAT P00750 1/20 0.34
TSHR P16473 3/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL224980 0.80 APLNR (0.58) APLNRCYP2C19LMNATSHRGABRP
SCHEMBL676895 0.80 APLNR (0.58) APLNRCYP2C19LMNATSHRGABRP
SCHEMBL1486693 0.77
SCHEMBL6567505 0.76 TSHR (0.44) APLNRCYP2C19LMNATSHRGABRP
SCHEMBL6704472 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA
SCHEMBL14561940 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA
SCHEMBL6418881 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA
SCHEMBL10086988 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA
SCHEMBL127229 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA
SCHEMBL4760572 0.74 TSHR (0.52) APLNRMEN1KMT2ACYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150219734-A1 POROUS AND STRUCTURED MATERIALS FOR DYNAMIC NUCLEAR POLARIZATION, PROCESS FOR THEIR PREPARATION AND NMR ANALYSIS METHOD UNIVERSITE CLAUDE BERNARD LYON I (FR) 2015-08-06 US disclosed
EP-2880458-A1 POROUS AND STRUCTURED MATERIALS FOR DYNAMIC NUCLEAR POLARIZATION, PROCESS FOR THEIR PREPARATION AND NMR ANALYSIS METHOD Université Claude Bernard Lyon I (FR) 2015-06-10 EP disclosed
WO-2014023659-A1 POROUS AND STRUCTURED MATERIALS FOR DYNAMIC NUCLEAR POLARIZATION, PROCESS FOR THEIR PREPARATION AND NMR ANALYSIS METHOD UNIVERSITE CLAUDE BERNARD LYON I (FR) 2014-02-13 WO disclosed