Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676895 | 0.86 | APLNR (0.58) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL224980 | 0.86 | APLNR (0.58) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL17586729 | 0.77 | TSHR (0.41) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL15568682 | 0.76 | APLNR (0.42) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL6567906 | 0.74 | GAA (0.31) | — | |
| SCHEMBL23590185 | 0.73 | APLNR (0.65) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL8318891 | 0.73 | APLNR (0.65) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL17212627 | 0.73 | APLNR (0.65) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL7178038 | 0.73 | APLNR (0.36) | APLNRMAOB | |
| SCHEMBL15304339 | 0.71 | GRM2 (0.50) | TSHRGRM2GRM3GRM4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265499-B1 | POLYMERIZING MIXTURE | MENICON CO., LTD. (JP) | 2001-07-24 | — | — | US | claimed |
| EP-0921134-B1 | Process for producing a shaped product | MENICON CO LTD (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6569968-B1 | Using polymerization catalyst | KURITA WATER INDUSTRIES LTD. (JP) | 2003-05-27 | — | — | US | disclosed |
| US-6265499-B1 | POLYMERIZING MIXTURE | MENICON CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1077200-A2 | Polymer of a water-soluble radical-polymerizable monomer, process for producing the polymer and flocculant comprising the polymer | KURITA WATER INDUSTRIES LTD. (JP) | 2001-02-21 | — | — | EP | disclosed |
| EP-0921134-A1 | Process for producing a shaped product | Menicon Co., Ltd. (JP) | 1999-06-09 | — | — | EP | disclosed |