Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 8/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | EED | O75530 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HLA-A | P04439 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15568451 | 0.84 | SSTR5 (0.66) | SSTR5KCNH2NR4A2LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL15568537 | 0.83 | SSTR5 (0.62) | SSTR5KCNH2NR4A2LMNAGAA | |
| SCHEMBL15569125 | 0.78 | PKM (0.60) | KCNH2LMNAHRH1HTTCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL15569147 | 0.78 | SSTR5 (0.64) | SSTR5KCNH2NR4A2LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL15568833 | 0.76 | LMNA (0.64) | SSTR5KCNH2NR4A2LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL15568655 | 0.73 | KMT2A (0.56) | KCNH2LMNAGAAALDH1A1HRH1 | |
| SCHEMBL15568207 | 0.73 | SSTR5 (0.69) | SSTR5KCNH2NR4A2LMNAGAA | |
| SCHEMBL15567989 | 0.73 | HRH1 (0.54) | KCNH2GAAALDH1A1HRH1MAPT | |
| SCHEMBL9698271 | 0.73 | SSTR5 (0.75) | SSTR5KCNH2NR4A2LMNAGAA | |
| SCHEMBL10529762 | 0.73 | SSTR5 (0.78) | SSTR5KCNH2NR4A2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027053-A1 | BENZIMIDAZOLES FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-02-20 | — | — | WO | disclosed |