Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350414 | 0.78 | CA12 (0.35) | HTR2AHTR2CHTR2BKDM4ES1PR4 | |
| SCHEMBL28446954 | 0.78 | CA12 (0.35) | MAPTNPSR1CA12CA1CA2 | |
| SCHEMBL7263826 | 0.77 | KDM4E (0.33) | HTR2AHTR2CHTR2BKDM4ES1PR4 | |
| SCHEMBL945659 | 0.77 | CA2 (0.35) | KDM4EMAPTMAPK1CA12CA1 | |
| SCHEMBL28582611 | 0.77 | CA12 (0.33) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL2348098 | 0.75 | HTR2A (0.33) | HTR2AHTR2CHTR2BKDM4ES1PR4 | |
| SCHEMBL22833910 | 0.75 | MAPT (0.43) | KDM4EMAPTMAPK1RAB9AMCL1 | |
| SCHEMBL28567295 | 0.75 | TP53 (0.35) | HTR2AHTR2CHTR2BKDM4ES1PR4 | |
| SCHEMBL6988996 | 0.75 | CA12 (0.32) | HTR2AHTR2CCA12CA1CA2 | |
| SCHEMBL27218671 | 0.75 | GAA (0.36) | HTR2AHTR2CHTR2BKDM4ES1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-2303863-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009158473-A1 | 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |