Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 4/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27924185 | 0.80 | CA2 (0.37) | CA2CA4TUBB1TUBB4ATUBB | |
| SCHEMBL28446954 | 0.80 | CA12 (0.35) | CA2CA4CA1CA9CA12 | |
| SCHEMBL28582611 | 0.78 | CA12 (0.33) | CA2CA4CA1CA9ACHE | |
| SCHEMBL27849022 | 0.77 | CA2 (0.34) | CA2CA4CA1SMN1; SMN2CA6 | |
| SCHEMBL27906216 | 0.77 | ALDH1A1 (0.37) | CA2CA4SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1556901 | 0.77 | HTR2A (0.33) | CA2CA4CA1CA9CA12 | |
| SCHEMBL22833910 | 0.77 | MAPT (0.43) | CA2CA1CA12MAPTTDP1 | |
| SCHEMBL6988996 | 0.77 | CA12 (0.32) | CA2CA4TUBB1CA1CA9 | |
| SCHEMBL28968102 | 0.76 | PDE4D (0.38) | TDP1 | |
| SCHEMBL28592643 | 0.76 | MAPT (0.44) | MAPTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001107-B | A kind of method of synthesizing methyl Hongmaoxinjian | 西安交通大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105001107-A | Synthetic method for methyl caulophine | UNIV XI AN JIAOTONG | 2015-10-28 | — | — | CN | claimed |
| US-5760051-A | CENTRAL NERVOUS SYSTEM | ELI LILLY AND COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| CN-118265453-A | Protein aggregation inhibiting compounds for plant disease control | 马克斯·普朗克科学促进学会 | 2024-06-28 | — | — | CN | disclosed |
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-3636636-B1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2022-07-06 | — | — | EP | disclosed |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-09-14 | — | — | US | disclosed |
| CN-107635981-B | Compounds and methods for inducing browning of white adipose tissue | 中国科学院广州生物医药与健康研究院 | 2020-08-04 | — | — | CN | disclosed |
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-06-04 | — | — | US | disclosed |
| EP-3636636-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | Mitsui Chemicals Agro, Inc. (JP) | 2020-04-15 | — | — | EP | disclosed |
| CN-105001107-B | A kind of method of synthesizing methyl Hongmaoxinjian | 西安交通大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105001107-A | Synthetic method for methyl caulophine | UNIV XI AN JIAOTONG | 2015-10-28 | — | — | CN | disclosed |
| US-8513260-B2 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-08-20 | — | — | US | disclosed |
| EP-2435420-B1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-04-03 | — | — | EP | disclosed |
| WO-2012164572-A1 | SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-12-06 | — | — | WO | disclosed |
| US-20120190687-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG | 2012-07-26 | — | — | US | disclosed |
| US-20110021539-A1 | Pyrazinylpyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | disclosed |
| US-6313153-B1 | ADMINISTERING PYRIDYLACRYLAMIDE COMPOUND FOR THERAPY OF NEPHRITIS | TSUMURA & CO. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1000935-A1 | PYRIDYLACRYLAMIDE DERIVATIVES AND NEPHRITIS REMEDIES AND TGF-$g(b) INHIBITORS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172486-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CBR3, CBR1 | CA2 986/4885CA4 1355/4885TUBB1 2184/4885 |
| US-20110021539-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | CA2 4362/4885CA4 4413/4885TUBB1 523/4885 |
| US-20120190687-A1 | Pyrazinylpyrazoles | CYP4F3, CYP4B1, CYP1A2 | CA2 4362/4885CA4 4413/4885TUBB1 523/4885 |
| US-11117863-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CBR3, CBR1 | CA2 986/4885CA4 1355/4885TUBB1 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.